What Is Biotechnology

What Is Biotechnology
The UN Convention on Biological Diversity states, “Biotechnology is any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use”. The OECD (the Organization of Economic Co-operation and Development) defines biotechnology as “…the application of scientific and engineering principles to the processing of materials by biological agents”. Therefore, “Biotechnology” basically means using biology as the idea for a technology that’s applied to research and products development in areas like agriculture, food science, and medicine.

The Tutorial Standards for Science and Technology defines Biotechnology as the ways that that humans apply biological ideas to supply merchandise and offer services. This is often terribly true if we tend to think about a section of biotechnology in which the directed manipulation of organisms is employed for the merchandise of organic product like beer, milk products, food etc.

Biotechnology had already been performed long before the term itself was coined, though on a very basic level. For instance, man had already learnt the tactic of fermenting fruit juices to concoct alcoholic beverages throughout the amount around 6000 BC. But, it had been thought of more of an art then. Biotechnology became a real science solely about two decades ago when genes were found to contain info that would enable the synthesis of specific proteins. This was in the Seventies, when new advances in the field of molecular biology enabled scientists to simply transfer DNA – the chemical building blocks that specify the characteristics of living organisms – between a lot of distantly related organisms.

Then in the mid-eighties and early-nineties, it absolutely was confirmed that the transformation or modification of the genetic structure of plants and animals was terribly possible. The introduction of “Transgenic” animals and plants additionally led to a lot of resistance to disease and increased the rate of productivity etc. Modern biotechnology is additionally now additional usually than not related to the employment of genetically altered microorganisms like E. coli or yeast for the production of substances like insulin or antibiotics. New innovative biotechnology application like plant-created pharmaceuticals has conjointly now been developed.

Sub-fields in Biotechnology:

Red Biotechnology is the utilization of genetically altered microorganisms for the assembly of drugs like insulin, antibiotics, vitamins, vaccines and proteins for medical use, and is therefore connected to medical processes. Genomic manipulation is also an example of Red Biotechnology.

Biomanufacturing or White Biotechnology is emerging field at intervals trendy biotechnology that involves the coming up with of organisms such as moulds, yeasts or bacteria, and enzymes to produce bound useful chemicals, and is related to the industrial sector. It’s additionally called Gray Biotechnology.

Inexperienced Biotechnology or agricultural Biotechnology, like the name suggests, is the area of biotechnology involving applications to agriculture. This essentially involves the genetic manipulation of plants and animals so as to form more productive, environmentally friendly, disease resistant species. An example of ancient agricultural biotechnology is the event of disease-resistant wheat varieties by cross-breeding different wheat sorts until the desired disease resistance variety is achieved.

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Question by : alittle help from people who know biology?? thank you!?
1. Restriction enzymes are useful in recombinant DNA studies because they:
a. can separate pieces of DNA and RNA from each other.
b. can reproduce in bacteria.
c. give plasmids antibiotic properties.
d. cut DNA only at specific locations.
e. join the cut ends of small DNA molecules.

2.Restriction enzymes:
a.can cut only bacterial DNA.
b. randomly cut DNA into small pieces.
c. produce single-stranded DNA fragments with “sticky ends.”
d. will cut DNA only if it contains methyl groups.

3.Which of the following applications of biotechnology results in an insect-resistant plant?
a. banana-based vaccine against pathogenic E. coli
b. Bt toxin production by soybeans
c. insulin production by bacteria
d. growth hormone-treated cows
e. herbicide-resistant corn

Best answer:

Answer by hcbiochem
1. d. cut DNA only at specific locations.

2. I don’t really like any of the 4 choices. a. is incorrect since restriction endonucleases can cut ANY DNA if it has the right sequence of bases. b. is incorrect because the enzyme cuts at absolutely specific sites…the cutting is not random. c. is incorrect because double-stranded DNA remains double-stranded after it is cut. d. is incorrect because for most restriction endonucleases, the presence of methyl groups blocks the ability of the enzyme to cut its sequences. Is there an e. choice that you didn’t include?

3. b. Bt toxin production by soybeans

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Posted by - January 29, 2012 at 4:46 am

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Biotechnology Timeline: Important Events And Discoveries In Biotechnology

Biotechnology Timeline: Important Events And Discoveries In Biotechnology

Article by George Royal

1977:

The Age of biotechnology arrives with “somatostatin” – a human growth hormone-releasing inhibitory factor, the first human protein manufactured in bacteria by Genentech, Inc. A synthetic, recombinant gene was used to clone a protein for the first time.

1978:

Genentech, Inc. and The City of Hope National Medical Center announce the successful laboratory production of human insulin using recombinant DNA technology. Hutchinson and Edgell show it is possible to introduce specific mutations at specific sites in a DNA molecule.

1979:

Sir Walter Bodmer suggests a way of using DNA technology to find gene markers to show up specific genetic diseases and their carriers. John Baxter reports cloning the gene for human growth hormone.

1980:

The prokaryote model, E. coli, is used to produce insulin and other medicine, in human form. Researchers successfully introduce a human gene – one that codes for the protein interferon- into a bacterium. The U.S. patent for gene cloning is awarded to Cohen and Boyer.

1981:

Scientists at Ohio University produce the first transgenic animals by transferring genes from other animals into mice. The first gene-synthesizing machines are developed. Chinese scientists successfully clone a golden carp fish.

1982:

Genentech, Inc. receives approval from the Food and Drug Administration to market genetically engineered human insulin. Applied Biosystems, Inc. introduces the first commercial gas phase protein sequencer.

1983:

The polymerase chain reaction is invented by Kary B Mullis. The first artificial chromosome is synthesized, and the first genetic markers for specific inherited diseases are found.

1984:

Chiron Corp. announces the first cloning and sequencing of the entire human immunodeficiency virus (HIV) genome. Alec Jeffreys introduces technique for DNA fingerprinting to identify individuals. The first genetically engineered vaccine is developed.

1985:

Cetus Corporation’s develops GeneAmp polymerase chain reaction (PCR) technology, which could generate billions of copies of a targeted gene sequence in only hours. Scientists find a gene marker for cystic fibrosis on chromosome number 7.

1986:

The first genetically engineered human vaccine – Chiron’s Recombivax HB – is approved for the prevention of hepatitis B. A regiment of scientists and technicians at Caltech and Applied Biosystems, Inc. invented the automated DNA fluorescence sequencer.

1987:

The first outdoor tests on a genetically engineered bacterium are allowed. It inhibits frost formation on plants. Genentech’s tissue plasminogen activator (tPA), sold as Activase, is approved as a treatment for heart attacks.

1988:

Harvard molecular geneticists Philip Leder and Timothy Stewart awarded the first patent for a genetically altered animal, a mouse that is highly susceptible to breast cancer

1989:

UC Davis scientists develop a recombinant vaccine against the deadly rinderpest virus. The human genome project is set up, a collaboration between scientists from countries around the world to work out the whole of the human genetic code.

1990:

The first gene therapy takes place, on a four-year-old girl with an immune-system disorder called ADA deficiency. The human genome project is formally launched.

1991:

Mary-Claire King, of the University of California, Berkeley, finds evidence that a gene on chromosome 17 causes the inherited form of breast cancer and also increases the risk of ovarian cancer. Tracey the first transgenic sheep is born.

1992:

The first liver xenotransplant from one type of animal to another is carried out successfully. Chiron’s Proleukin is approved for the treatment of renal cell cancer.

1993:

The FDA declares that genetically engineered foods are “not inherently dangerous” and do not require special regulation. Chiron’s Betaseron is approved as the first treatment for multiple sclerosis in 20 years.

1994:

The first genetically engineered food product, the Flavr Savr tomato, gained FDA approval. The first breast cancer gene is discovered. Genentech’s Nutropin is approved for the treatment of growth hormone deficiency.

1995:

Researchers at Duke University Medical Center transplanted hearts from genetically altered pigs into baboons, proving that cross-species operations are possible. The bacterium Haemophilus influenzae is the first living organism in the world to have its entire genome sequenced.

1996:

Biogen’s Avonex is approved for the treatment of multiple sclerosis. The discovery of a gene associated with Parkinson’s disease provides an important new avenue of research into the cause and potential treatment of the debilitating neurological ailment.

1997:

Researchers at Scotland’s Roslin Institute report that they have cloned a sheep–named Dolly–from the cell of an adult ewe. The FDA approves Rituxan, the first antibody-based therapy for cancer.

1998:

The first complete animal genome the C.elegans worm is sequenced. James Thomson at Wisconsin and John Gearhart in Baltimore each develop a technique for culturing embryonic stem cells.

1999:

A new medical diagnostic test will for the first time allow quick identification of BSE/CJD a rare but devastating form of neurologic disease transmitted from cattle to humans.

2000:

“Golden Rice,” modified to make vitamin A. Cloned pigs are born for the first time in work done by Alan Coleman and his team at PPL, the Edinburgh-based company responsible for Dolly the sheep.

2001:

The sequence of the human genome is published in Science and Nature, making it possible for researchers all over the world to begin developing genetically based treatments for disease.

2002:

Researchers sequence the DNA of rice, and is the first crop to have its genome decoded.

2003:

The sequencing of the human genome is completed.

Biotechnology HQ: articles and information about the science of biotechnology.










Question by marc d: BIOTECHNOLOGY in PH!?
i need help about our subject BIOTECH. our teacher asked us to find the timeline of BIOTECHNOLOGY HERE IN THE PHILIPPINES because we studied BIOTECH IN THE WORLD. for exmple, on 1683 leeuwenhoek dscovered the microscope just like that. i need the list of the inventions/products/discovery of BIOTECH here in the PHILIPPINES from 5000BC-present. it would really be a big help if you would help me even if ull just gve xmples. TEN BIG POINTS for the best answer!

Best answer:

Answer by NextRightGuy
http://www.hg.org/law-firms/Biotechnology/Philippines.html

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Posted by - January 29, 2012 at 1:01 am

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Decisions that Make a Difference about your 401k Rollover

Frequently, the words IRA rollover as well as 401(k) rollover are employed interchangeably because people utilize both words to describe the transfer of cash from a 401k plan to an IRA whenever they either change companies or cease working. The main reasons it is popular to transfer funds from the 401k plan when separating from the company is for the greater selection of investments and also perhaps superior investment results as well as increased control of your retirement funds. The typical 401k may provide Four to Ten investment options whilst your IRA which is nearly limitless regarding your investment alternatives. In reality, a lot of people working for a company will attempt to transfer dollars from their 401k to their IRA to enjoy these types of advantages and in some cases that may be possible.

The way you take care of the particular mechanics of your 401k roll-over is very important since the wrong way can lead to unwanted withholding tax. When moving dollars from your 401k to an IRA, you may receive the check from the 401k administrator after which you bring it to your new IRA custodian otherwise you can have the 401k manager send out the funds directly to the IRA account. The first choice is a bad alternative as the 401kmanager must hold back 20% of the balance in the event the check is being delivered to you. In the event the 401(k) rollover is conducted directly between the 401k administrator and your new IRA custodian, zero withholding is necessary.

Whenever transferring funds from the 401k to an IRA rollover, it is occasionally valuable not to roll over all financial assets. Specifically, stock of your employer that you have inside your 401k as you can get beneficial tax treatment if you take these shares out of your 401k and do not roll them over. Specifically, a great deal of the profit on those shares may very well be eligible for capital gains tax. But if you rollover the stock to your IRA, the advantage will disappear permanently.

Sometimes, the words IRA rollover is used to identify the transfer regarding funds from a single IRA account to a new one. Here yet again, you may either receive a check from one IRA and hand it to your other or have the previous IRA custodian send the funds directly to your new IRA custodian. The latter is really a more effective solution to handle an IRA rollover since it reduces the risk for almost any problems that could result in unnecessary taxes to you. While there is zero withholding when you get dollars from an IRA bill, you will need to finish the IRA rollover within Sixty days or the distribution becomes taxed to you.

Observe that all dollars taken from a IRA or 401k is not qualified for rollover. As an example, whenever you become age 70 1/2, you are confronted by obligatory withdrawals from either kind of account. When taking those obligatory withdrawals, they are reported on your tax return and are then subject to taxes. You may not do a IRA rollover of these funds since they are not eligible

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Posted by postlinks - January 26, 2012 at 6:04 am

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